Updates

• September 2020: Almost a year with no writing and for a good reason! I won’t be doing anything related to synergy in my PhD, expect from this analysis. This means this is going to be left as it is for now, the full notes are still available in the Word doc if you wanna check them out. Sorry :(
• Summer 2020: Read an amazing review article about synergy models (Meyer et al. 2020), not so much from the mathematical perspective, but much more broad and interesting! It introduced to several other mathematical formulas which I wasn’t aware of when I wrote the notes, so more reading, more writing!
• November 2019: I thought of making this as a bookdown (Xie 2020) document since it would be nicer to have it in that format for online reading, boost it’s accessibility to the scientific community and add a means to collaborate (via Travis + bookdown’s Edit button). It’s gonna take some time to write it down though from the Word document
• Summer 2018: I read a bunch of papers related to synergy quantification and models that describe it and wrote a Word document with my notes. My motivation is to understand the mathematics behind the different models that are used to computationally assess synergy, antagonism or non-interaction between drugs that are tested in high-throughput screens, and compare/assess their weak and strong points.